HI,was just wondering if anyone on mtx had developed a serious rash i have and it drives me nuts, ive been niggling doctors for a year now, after lots of creams,ive got a refferal to the dermatologist at last, but i wondered if anyone had reacted the same way to mtx. also i am on co-codomols and if anyone got a rash to them,they do make me itch if i take 2 at the same time i have to spread them out over tha day and that helps.